Figure 1. Motor neuron
Resting membrane potential
Depolarisation
Figure 2. Membrane potential changes during an action potential, demonstrating the opening and closing of voltage-gated Na+ and K+ ion channels.
Figure 3. Release of acetylcholine at the cholinergic synapse. Acetylcholine is synthesised from acetyl Co-A and choline and transported into synaptic vesicles by VAT. When the action potential reaches the terminal bouton, voltage-gated Ca2+ channels open and the influx of Ca2+ down its electrochemical gradient causes the vesicle to fuse with the pre-synaptic cell membrane and release its contents through exocytosis.
Nerve structure and function
Question :What are the major events that occur in neuromuscular transmission
Question: Can you draw me out a neuromuscular junction?
Figure 4.Candidate drawing neuromuscular junction
Concerning the neuromuscular junction (motor end plate)
QUESTION ID: 1052
What type of afferent peripheral nerve fibre is responsible for transmitting vibration sense to the spinal cord?
QUESTION ID: 1274
During a neurological examination, a patient has an absent knee jerkWhich primary afferent fibres normally mediate the myotactic reflex?
QUESTION ID: 1305
A catheterised man with suspected cauda equina syndrome has their catheter tugged, during a per rectal examination. Which nerve is responsible for the afferent arm of this pathway?
QUESTION ID: 1306
A catheterised man with suspected cauda equina syndrome has their catheter tugged, during a per rectal examination.
Which nerve is responsible for the efferent arm of this pathway?
QUESTION ID: 1307
A diabetic patient is unable to feel the tuning fork, during a neurovascular examination. Which afferent nerve fibres have been affected?
QUESTION ID: 1308
A diabetic patient is unable to feel the tuning fork, during a neurovascular examinationWhich cell type is responsible for detecting this sensation modality?
QUESTION ID: 1309
A digital nerve is transected by a kitchen knife, and subsequently repaired. What is the greatest determinant of healing after surgical repair of a nerve?
QUESTION ID: 1310
56.Concerning the ionic mechanism at work with nerve action potentials
QUESTION ID: 3253
2024 Postgraduate Orthopaedics All rights Reserved